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Intrinsic factor is efficient at absorbing a high percentage of a small dose of B12, but it becomes saturated after a meal containing an above-average amount of B12, and about 4 to 6 hours are required before it can efficiently absorb another dose (Institute of Medicine, 1998)

Fasting glucose, HbA1c, liver function, kidney function, and lipid panels inform your provider's decision on safe starting doses, monitoring frequency, and any dose adjustments

Rare or Serious Side Effects Rare or serious side effects documented in research include blood pressure effects with hypotension reported at very high doses