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Catalano PM, Shankar K

Additionally, in addition to targeting neuronal cells, targeting immunometabolic reprogramming in astrocytes to prevent neuroinflammation may present a new avenue for ND treatment, necessitating the differentiation of various cell types within the substance

ICD9CM: 787.01, 787.03, 536.2

This interaction ultimately diminishes the transcriptional activity of the NF-B complex, and as a result, SIRT1-mediated deacetylation serves to inhibit NF-B signaling