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These include: Semaglutide (Wegovy) recommended by NICE for weight management in eligible adults (NICE TA875) Liraglutide (Saxenda) recommended by NICE for weight management in selected groups (NICE TA664) Orlistat available for weight management under NICE guidance (NICE CG189) Naltrexone/bupropion (Mysimba) does not currently have a positive NICE recommendation for weight management in England and should not be assumed to be a routinely recommended option

Like alcohol use, chronic GHB use can lead to tolerance, dependence, addiction, and withdrawal symptoms