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Also identified was increased risk of abdominal pain, gastroesophageal reflux disease (GERD), gastritis, non-infectious gastroenteritis, gastroparesis, diverticulosis, diverticulitis, low blood pressure, fainting, sleep disturbances, headaches, arthritis and joint pain, tendinitis, and kidney problems (interstitial nephritis and nephrolithiasis), gallstone formation and gallbladder inflammation

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Studies suggest that this combination produces greater weight reduction, improved glycemic control, and favorable body composition changes compared to monotherapy