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Therefore, neurons are the first cells that appear to be affected by oxidative stress [28]

While TMT-induced neurotoxicity and cognitive impairments in animal models can provide insights into certain aspects of neurodegeneration and memory deficits, AD is a complex and multifactorial disease with genetic, environmental, and age-related factors playing significant roles

The sequential approach The ATTAIN-MAINTAIN trial introduces a compelling treatment strategy: using tirzepatide and orforglipron sequentially rather than choosing one or the other

The most common side effects are mild, including nausea, vomiting, bloating, constipation and diarrhea