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Palmer SC, Tendal B, Mustafa RA et al (2021) Sodiumglucose cotransporter protein-2 (SGLT-2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists for type 2 diabetes: systematic review and network meta-analysis of randomised controlled trials

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Baicalin offers a potentially safer alternative to synthetic JAK inhibitors, although challenges remain regarding solubility, extraction standardization, and the lack of robust clinical validation [45]