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[DOI] [PubMed] [Google Scholar] 152.Yoshioka N, Ishigami M, Watanabe Y, Sumi H, Doisaki M, Yamaguchi T, et al

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For example, mutations in skin barrier-related genes (such as filaggrin) can lead to increased transdermal water loss and downregulated expression of tight junction proteins, thereby enhancing the skins permeability to MPs

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