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Enhanced Energy Expenditure via NNMT Inhibition : In preclinical models, 5-Amino-1MQ increased whole-body metabolic rate by redirecting cellular resources away from fat storage and toward active ATP production

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Whether this observation is solely the consequence of translocation of Parasutterella bacteria from the intestine to the EWAT or driven by more indirect mechanisms such as bacterially-produced metabolites 85 is yet to be determined