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OGD/R model The OGD/R model was established in N9 microglia according to previously described methods [13].For oxygen-glucose deprivation, microglia were maintained in D-Hanks solution with a humidified anaerobic incubator (Thermo 3111

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On the one hand, microglial activation promotes the release of pro-inflammatory cytokines, such as IFN-, IL-6, TNF- and IL-1, and aggravates ischemic injury