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Carbone G, Wilson A, Diehl SA et al (2013) Interleukin-6 Receptor Blockade Selectively Reduces IL-21 Production by CD4 T Cells and IgG4 Autoantibodies in Rheumatoid Arthritis

So, to me, the pain is worth it

Formation of islet amyloid fibrils in beta-secretory granules of transgenic mice expressing human islet amyloid polypeptide/amylin

In 3T3-L1 adipocyte cell models, 5-Amino-1MQ at 30 M concentration produced significant reductions in intracellular 1-MNA levels, confirming target engagement