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The synthesis of reactive oxygen species with the involvement of inflammatory response cells is carried out by enzymes such as NADPH oxidase

Compound 2 (5.4 g, 9.72 mmol), H-Lys(Boc)-OMeHCl (3.46 g, 11.52 mmol), HATU (7.42 g, 19.44 mmol) and HOAT (2.64 g, 19.44 mmol) were dissolved in DMF (80 mL) under nitrogen atmosphere and ice bath conditions

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Heavy metals (including lead, cadmium, mercury, and the metalloid arsenic) are persistent in the environment and have documented potential for serious health consequences