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Statistical analyses were performed by SPSS23.0 (SPSS Inc., Chicago, USA) and GraphPad Prism 7 (GraphPad Software, San Diego, USA)

Establish a specific weight range (typically 5 to 10 pounds above your goal weight) that triggers action if exceeded

It activates GHS-R1a (the target receptor for GH release) but also cross-reacts with receptors that elevate adrenocorticotropic hormone (ACTH), cortisol, and prolactin