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M.TanJ.et al (2020)

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Another potent oral PARP1/2 inhibitor, niraparib (MK4827) binds to the active site of PARP enzymes, and studies indicate that Niraparib can restore NAD + levels and improve mitochondrial function 165,166

Based on research by Ali et al, 6-gingerol decreases the development of NETs significantly in lupus models, therefore being protective against the cardinal pathological features associated with lupus-inflammation and autoantibody formation