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The best protocol is one that matches your goals, your biology, your tolerance profile, and your providers clinical assessment
Researchers investigated four different titration and monthly dose groups compared with placebo: 0.4 mg to 0.8 mg weekly to 3.2 mg monthly
Given how hard it is to get these medications for some patients, this can be an attractive alternative, but the FDA has expressed concern at the frequency of -glutide salts turning up in compounded formulations, which are not present in any of the FDA-approved drugs and thus have an unknown safety and efficacy profile
However, those already on blood pressure medications should be monitored closely, as GLP-1-induced blood pressure reductions could necessitate antihypertensive dose adjustments to prevent hypotension or orthostatic symptoms
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