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This case particularly highlights an uncommon presentation with hypercalcemia and cutaneous metastases that may not be recognized as a manifestation of CCS by an oncologist who does not specialize in sarcomas

The virus may also replicate in peripheral blood mononuclear cells, potentially accounting for the high levels of immunological disorders found in chronically infected HCV patients

Both open (Protein Data Bank (PDB) 3KAK) and closed (PDB 3KAL) active site forms of hGSH synthetases have been crystallized, with the phosphorylation and amide bond-forming steps proposed to be catalyzed in the closed form 52

Jan;12(1):37-51