semaglutide step Once-weekly 7·2 mg in adults with obesity (STEP UP): a randomised, controlled, phase 3b trial Key eligibility criteria for STEP

This creates a disparity where only those who can afford the long-term cost can maintain their weight loss results

2018;97:e13902

The move also ties in with efforts by the broader pharma industry to move away from the unpopular system of high list prices for medicines that are then subject to opaque rebates and reductions by supply chain middlemen like pharmacy benefit managers

These molecules are typically found in Sauvignon blanc from New Zealand at several-fold higher concentrations that in the same variety produced elsewhere, and when scientists went looking for the reason they found an unexpectedly complicated story