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doi: 10.1038/nrn3113 171 GohWWBWangWWongL

(PubMed) Reiss GR, Werness PG, Zollman PE, Brubaker RF

The most common adverse effects of tirzepatide are gastrointestinal, including nausea (occurring in 15-30% of patients), diarrhea, vomiting, constipation, and abdominal discomfort