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Trends Endocrinol Metab 2016;27:427-38.ArticlePubMed 32

These findings suggest that the cardioprotective effects of semaglutide extend beyond its impact on adiposity, with important implications for clinical practice and understanding of the mechanisms responsible for the benefits from GLP1-Ras, John Deanfield (University College London, London, UK) and colleagues write in their Lancet paper detailing the results

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This paradigm shift has important implications for treatment durationjust as patients with hypertension or diabetes require ongoing medication management, individuals with obesity may need continuous pharmacological support to maintain weight loss and associated health benefits