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[35] [36] [37] Therefore, these effects can be connected to decreased insulin-like-3 (INSL3) hormone, which controls transabdominal testicular descent, decreased androgen production in the testicles, which is essential for male sexual development, and disruption of seminiferous cord formation, Sertoli cells, and germ cell development via an unknown mode of action (MOA)

The hormone also slows so-called gastric emptying, or the process by which the contents of the stomach are moved into the small intestine

This trend highlights a gap between evidence-based medicine and everyday practice

Some patients benefit from remaining at a lower dose for an additional week or two before escalating further