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Seek medical advice if you experience: Severe or persistent abdominal pain that does not go away Black, tarry, or bloody stools (a sign of potential GI bleeding) Vomiting blood or material that looks like coffee grounds A significant decrease in urination or swelling in your ankles/feet Signs of an allergic reaction, such as a rash, itching, or swelling Always disclose all medications, including supplements and over-the-counter pills, to your healthcare provider during your initial assessment and ongoing check-ins

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For individuals with pre-existing cardiovascular conditions, long-term use could potentially exacerbate these issues

[1] [2] Breastfeeding: GLP-1 medications are not recommended during breastfeeding