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Leptin is produced not only in the adipose tissue but also in the gastrointestinal tract, particularly in the stomach, where it has been shown to protect the gastric mucosa against various topical irritants and ulcerogens, acting, at least in part, via enhancement of mucosal blood flow due to increased production of nitric oxide (NO) caused by upregulation of NO synthase as well as the activation of brain-gut axis pathways (48, 49)
Tirzepatida tiene un buen perfil de seguridad y aporta mejoras cardiometablicas en los niveles de colesterol, hipertensin y permetro de cintura, entre otros indicadores 1-4
Supplied in lyophilized form for convenient storage and handling in research settings
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