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[9] Depending on this modified state, FOXO4 binding affinity for DNA is altered, allowing for FOXO4 to regulate many cellular pathways including oxidative stress signaling, longevity, insulin signaling, cell cycle progression, and apoptosis

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J Toxicol 2013:19

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SGLT2 inhibitors Those with breast cancer and type 2 diabetes using SGLT2 saw a 5-year survival rate of 88.9% and a 10-year survival rate of 73.4%

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