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Coverage through employer-sponsored insurance is increasingly common, highlighting the broader shift toward GLP-1 medications for weight management

The appetite suppression GLP-1 medications produce works independently of thyroid function

The concomitant use of alcohol or central nervous system (CNS) depressant drugs (e.g., barbiturates, benzodiazepines, and sleep medications) with phentermine or topiramate may potentiate CNS depression or other centrally mediated effects of these agents

Most cases are classified as mild to moderate in intensity and typically resolve within the first few weeks of therapy as the body adapts to the medication