doi: 10.1523/JNEUROSCI.3632-07.2008 203 WangX
L., Heij, L., Vogels, O., van Velzen, M., Sarton, E., Niesters, M., Tannemaat, M
Journal: The Lancet Year: 1982 Link: Access the study on ScienceDirect Summary: This study demonstrated that Sermorelin (GHRH 129) effectively stimulates growth hormone secretion in children with growth hormone deficiency, leading to improved growth rates
Notably, the STEP (Semaglutide Treatment Effect in People with obesity) trials, which specifically examined body composition, demonstrated substantial weight loss compared with placebo (NCT03548935) [53], and reductions in fat mass and visceral adipose tissue were accompanied by decreases in lean mass, although the proportion of lean mass relative to total body mass increased (NCT04074161) [54]