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Mller TD, Finan B, Clemmensen C, et al
KoopmanRCrombachNGijsenAPWalrandSFauquantJKiesAKet al
Overall, this results in the elution of sample molecules with the lowest exposed hydrophobicity first, followed by those with more exposed hydrophobicity
These include dopamine and its catabolites, several other types of amine or amino acid neurotransmitters, neuropeptides, oxidative damage markers, purine catabolite like uric acid, inflammatory markers, neurotrophic factors like brain-derived neurotrophic factor (BDNF), microRNAs, and several proteins known to be associated with the pathogenesis of PD and other neurodegenerative disorders, and all these have been discussed elaborately in multiple reviews and meta-analyses (Jimnez-Jimnez et al., 2014
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