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4) Pharmacokinetics & Safety (Preclinical) In animals, intravenous and intramuscular dosing provide systemic exposure with a relatively short elimination half-life

Therefore, we quantified ALT activity using the c-circle assay and confirmed the result with immunofluorescence (IF) to detect PML bodies

Additionally, HDACi can promote the secretion of cytokines such as IL-2 and IFN-, thereby enhancing T cell proliferation and effector functions (82, 83)