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the Food and Drug Administration (FDA) has actually issued a safety alertabout this the variety in size and gauge can impact how much insulin youre dosing the tiny size and need to twist onto insulin pens can be challenging to those with limited finger movement FDA labeled to be used only once and then disposed of theres always a chance with a pen needle (or any syringe and insulin pump infusion set) to hit muscle tissue that causes pain or bleeding For the newly diagnosed, thinking about having to inject yourself with insulin multiple times a day can be daunting