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Studies in thyrotoxic rats suggest that the oxidative stress may be involved in the pathogenesis of thyrotoxic myopathy and cardiomyopathy (26) and in vitro studies have shown that exposure of thyroid cell to H 2 O 2 , particularly when made selenium-deficient, induces DNA double strand breaks, apoptosis, necrosis and mutagenesis (24)
Vidal-Alaball J, Butler CC, Cannings-John R, Goringe A, Hood K, McCaddon A, McDowell I, Papaioannou A
[DOI] [PMC free article] [PubMed] 448.de la Harpe KM, Kondiah PPD, Choonara YE, Marimuthu T, du Toit LC, Pillay V
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