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Multi-omics of Gut Microbiome-Host Interactions in Short- and Long-Term Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients

Similar to scrapie, -synuclein pathology spreads in the peripheral and enteric nervous systems, then to CNS, whereas Alzheimers tau pathology propagates within the CNS only, beginning in the brainstem then involving cortical areas in a characteristic pattern (Braak and Del Tredici, 2016