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1-MX is a natural dietary ingredient that can be found in several different foods, such as garden tomatoes ( Solanum lycopersicum ), lotus ( Nelumbo ), okras ( Abelmoschus esculentus ), tamarinds ( Tamarindus indica ), chestnuts ( Castanea ), white tea ( Camellia sinensis L.) [15, 16], cacao ( Theobroma cacao ) [17] and coffee ( Coffea eugenioides , Coffea bengalensis ) [18]

10.1007/s002280050525 5 BalenovicD.BencicM

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Notably, pDCs are the major producers of IFN- in SLE, and IFN- production from pDC mediated by TLR9 is reduced by mTOR inhibitor, which regulates pDC differentiation and activation by modulating mitochondrial biogenesis and energy metabolism (78)