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YAP quickly creates an intradomain disulfide bond between Cys310 and Cys315 (disulfide bond 1) within 10 s to 5 min under 0.5 mM H 2 O 2 exposure

As noted by the American Association for the Study of Liver Diseases (AASLD): "Drug-induced liver injury remains a diagnosis of exclusion, and re-challenge with the suspected agent should be avoided in cases of serious hepatotoxicity" [8]

found that neutrophils exhibit reduced velocity and increased adhesion to vascular walls during ischemia-reperfusion

Acknowledgements This research was supported by National Key R&D Program of China (2021YFF0702600), the National Natural Science Foundation of China (82222056 and 82111530099), Guangdong Special Young Talent Plan of Scientific and Technological Innovation (2019TQ05Y510), the Natural Science Foundation of Guangdong (2022A1515012316), the Guangdong International Joint Research Program (2020A0505100027), and National Key Clinical Discipline