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Specifically, they observed elevations in: Acetylcholine: Critical for memory formation and cognitive processing Dopamine: Essential for motivation, focus, and reward GABA: The brain's primary inhibitory neurotransmitter These changes in neurotransmitter levels were consistent across both young and aged animals, though young animals generally exhibited higher baseline levels of all neurotransmitters compared to their older counterparts

Additionally, Pycnogenol can modulate levels of certain neurotransmitters theres evidence it can increase glutathione (a key brain antioxidant) and affect catecholamine metabolism

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Yin XY, Cheng H, Wang WJ, Wang WJ, Fu HY, Liu LH, et al