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It has been detected that DSIP (Delta Sleep-Inducing Peptide) reduced the nocturnal activity of an enzyme, NAT, and might also be involved in the modulation of adrenergic transmission

Pickart 2015 BioMed Res Int sequenced by Affymetrix chip the effects of 10 nM GHK-Cu on human fibroblasts after 24h: 4192 significantly modulated genes, including activation of DNA repair programmes (NBN, BRCA1), regeneration (collagens, elastin, integrins), antioxidant defence (glutathione peroxidase, SOD, peroxiredoxins) and anti-inflammatory modulation (reduction of TNF-alpha, IL-6, IL-8)

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However, the same receptors are found in other parts of the body and can bind to compounds