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A comprehensive review should assess: Glycaemic control Renal health Cardiovascular risk Microvascular complications Medication safety and adherence Lifestyle and psychosocial factors For primary care clinicians, a structured diabetes review helps identify complications early, improve treatment safety, and support long-term cardiovascular and renal health

Patient Readiness and Expectations The successful introduction of GLP-1 depends on patient understanding, psychological readiness, and long-term commitment: Mechanism Awareness: Patients must understand that GLP-1 facilitates a caloric deficit and is not a substitute for dietary and lifestyle management

The other incretin hormone, glucose-dependent insulinotropic polypeptide (GIP), generally shows impaired insulinotropic activity and limited glucose-lowering effectiveness in type 2 diabetes (T2D)

D-psicose inhibits intestinal -glucosidase and suppresses the glycemic response after carbohydrate ingestion in rats