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If the powder still has not dissolved after 30 minutes of periodic gentle swirling, the powder may have degraded from improper storage (exposure to heat, moisture, or extended room temperature storage)
Philp and colleagues (FASEB J, 2003, PMID 14500546) showed the LKKTETQ actin-binding motif at residues 17 to 23 is sufficient to promote endothelial cell migration in aortic ring and chorioallantoic assays, and Bock-Marquette and colleagues (Nature, 2004, PMID 15565145) reported integrin-linked kinase and Akt activation in mouse cardiac models