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All studies were interventional, meaning they actively tested GLP-1 as a treatment intervention rather than simply observing existing conditions

Melanocytes in the skin have more accessible iron than keratinocytes

Specifically, they observed elevations in: Acetylcholine: Critical for memory formation and cognitive processing Dopamine: Essential for motivation, focus, and reward GABA: The brain's primary inhibitory neurotransmitter These changes in neurotransmitter levels were consistent across both young and aged animals, though young animals generally exhibited higher baseline levels of all neurotransmitters compared to their older counterparts

Chronic hyperglycemia in diabetes is closely linked to a persistent inflammatory response, which aggravates neuronal damage and cognitive decline 51,52