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In this review, we focused on the correlation of the gut microbiota with RE and aimed to assess recent microbiome-based therapies for this disease

As we have reviewed, many multi-omics studies in pome and stone fruit CI have created CI development models involving candidate genes, however, further research is required to validate them to further apply them in breeding programs

Regarding the mechanism of PBMs action on chondrocytes, studies confirm that PBM upregulates the gene and protein expression of type II collagen and aggregated proteoglycans, significantly promoting chondrocyte proliferation and activity (42)

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