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This cascade precipitates tumor immune evasion through multifaceted mechanisms: functional impairment of effector immune cells, amplified secretion of immunosuppressive cytokines, upregulation of immune checkpoint molecules, and altered tumor-associated antigen presentation (1214)

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doi: 10.1016/j.cell.2009.04.050 198 VasevaAVMarchenkoNDJiKTsirkaSEHolzmannSMollUM

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