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Potential cardiovascular benefits

An external solution of 140 mM NaCl, 5 mM KCl, 1 mM MgCl 2 , 2 mM EGTA, 10 mM HEPES, and 10 mM glucose, adjusted to pH 7.4 with NaOH, osmolarity 300310 mOsm, was used for both techniques

The breadth of documented activity reflects what the original investigators have described as systems-level pharmacology: rather than acting through a single high-affinity receptor, BPC-157 appears to modulate multiple intersecting cellular pathways including nitric oxide signalling, growth-factor receptor expression, dopamine and serotonin metabolism, and angiogenic vessel formation