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The peptide has also been studied in the context of retinal degeneration, where it showed protective effects on retinal pigment epithelium in models of age-related macular degeneration

We and others have previously characterised these in vitro models of CRC, demonstrating SW837 rectal cells as a robust model of radioresistant rectal cancer (23, 48, 49)

Furthermore, ammonium metabolism suppresses immune cell effector functions, including cytotoxicity, by altering their energy metabolic pathways, thus providing a favorable growth environment for tumor cells