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The Paris Fire Brigade reported that between 1995 and 2003, there was a 41.7% survival rate for 72 patients exposed to cyanide-poisoning through smoke inhalation, and within this group 9 of the the 12 patients with increased systolic blood pressure (bp) treated with hydroxocobalamin demonstrated a recovery of systolic bp to normal (Fortin, 2006)
The research community needs well-designed human pharmacokinetic studies before efficacy trials make sense
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