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Overview of Efficacy, Side Effects, and Key Challenges GLP-1 receptor agonists such as semaglutide and liraglutide, as well as combination agents like tirzepatide (which adds glucose-dependent insulinotropic polypeptide receptor agonism)all hereafter referred to as GLP-1s for brevityare effective new agents for obesity treatment which demonstrate weight reduction, weight maintenance, and reduced morbidity and mortality

Regular blood testing ensures treatment effectiveness and allows for necessary adjustments to maintain optimal B12 levels

retinoids), and injectable safety