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Report persistent vomiting, severe abdominal pain, or signs of pancreatitis to your GP urgently, and use the MHRA Yellow Card scheme for suspected adverse reactions

Many compounded formulations include B12 , glycine , or niacinamide to offset this effect and improve tolerability

Reconstituted storage Once mixed with bacteriostatic water, GHK-CU requires refrigeration at 2-8C (35-46F)

At the category level, mild localized skin redness or itching at the application site is the most commonly reported issue with adhesive patches of any kind - this typically comes from the adhesive material, not the botanical ingredients themselves