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A panel of C-terminally truncated variants, including Syn 1131 , Syn 1121 , Syn 1103 , and N-terminal (His) 6 -tagged Syn WT constructs, was generated using Syn WT construct as the template 73

Cell surface biotinylation further showed ZIP8 and ZIP14 on both membranes of human brain microvascular endothelial cells (hBMVECs), with ZIP8 more abundant apically and ZIP14 basolaterally, though not statistically significant (Steimle et al., 2019)

The drugs work by helping the pancreas increase production of insulin to move sugar from the blood into body tissues

Once discontinued, many patients experience appetite rebound, making sustained weight loss challenging