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9 Nrf2 is usually locked in the cytoplasm, but activation by DMF/MMF allows it to translocate to the nucleus where it activates a pathway of genes involved in antioxidant responses, detoxification, and the activity of cytoprotective anti-inflammatory factors

Studies have shown that people with Hashimotos and hypothyroidism often do not have adequate levels of stomach acid , and some dont produce ANY stomach acid, making protein digestion inefficient and even more draining of our energy

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The dasatinib-plus- quercetin combination cleared senescent cells in a first-in-human trial, and a small feasibility trial is testing it in Alzheimers, though the brain evidence is early