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Other research, including a 2025 study published in Nature Medicine , has explored potential links between GLP-1 use and lower risks of conditions such as substance use disorders and dementia

Clinical trials assessing the effects of GH treatment in patients with obesity have shown consistent reductions in total adipose tissue mass, in particular abdominal and visceral adipose tissue depots

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Existence of genetic variants of thiamine-dependent proteins, insufficient molecular identification of these proteins, as well as the age- and sex-dependent differences in thiamine metabolism (30), may contribute to the observed variety of clinical manifestations of thiamine deficiency (31, 32)