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Pathway 1 - Mitochondrial Fat Oxidation (AMPK) MOTS-c activates AMP-activated protein kinase (AMPK) , the energy sensor that flips muscle cells from preferring glucose to preferring fat

doi:10.3945/ajcn.111.013458 Ermens AA, Vlasveld LT, Lindemans J

suggests that TB-500 may shape cell movement as it binds globular actin (G-actin) and may adjust how actin filaments assemble to plausibly render cells more capable of changing shape, migrating, and organizing into multicellular structures

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