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Specific targeting of LIGHT/TNFSF14 to tumor vessels using vascular targeting peptides improved vessel functionality, activated endothelial cells and induced formation of HEV in murine glioblastoma, associated with enhanced accumulation of lymphocytes [333]

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That growth has already been enjoyed by shareholders of the companies dominating that space, including Novo Nordisk NYSE: NVO, maker of Ozempic and Wegovy, and Eli Lilly NYSE: LLY, maker of Zepound and Mounjaro

The publication reported the estimated mean percent change in body weight from baseline to week 68 for each arm, with the combination arm showing a substantially larger estimated reduction than placebo, and the cagrilintide-alone arm showing an intermediate reduction