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Description

B., Olde Damink S

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As monotherapy , a multicentre, randomised, double-blind, placebo-controlled and active-controlled Phase 2 dose-finding trial enrolled 706 adults with overweight or obesity (without diabetes) to once-weekly subcutaneous cagrilintide across doses of 0.3 to 4.5 mg over 26 weeks

This dual action of promoting fat breakdown while simultaneously reducing fat storage creates the net effect of adipose tissue reduction, all occurring at the peripheral tissue level without involvement of central appetite-regulating pathways in the hypothalamus