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Because the signal originates at the receptor level, it bypasses hypothalamic and pituitary regulatory layers

It is estimated that of those with a history of gestational diabetes, about HALF go on to develop type 2 diabetes

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Ouyang H, Zhu H, Li J et al (2022) Fumonisin B(1) promotes germ cells apoptosis associated with oxidative stress-related Nrf2 signaling in mice testes